Bioactivity:

Quiflapon causes cell apoptosis. Quiflapon is a selective and specific 5-lipoxygenase-activating protein (FLAP) inhibitor (IC50: 1.6 nM in a FLAP binding assay) and is also an effective and orally active Leukotriene biosynthesis (LT) inhibitor (IC50: 3.1

CAS nr:

136668-42-3

Purity:

98%

Molecular Weight:

587,17

SMILES:

CC(C)(C)Sc1c(CC(C)(C)C(O)=O)n(Cc(cc2)ccc2Cl)c(cc2)c1cc2OCc1nc2ccccc2cc1

Formula:

C34H35ClN2O3S

Pathway:

Immunology/Inflammation,Apoptosis

Target:

FLAP,Apoptosis