Bioactivity:

Droxinostat is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 _M and 1.46 _M, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10.

CAS nr:

99873-43-5

Purity:

98%

Molecular Weight:

243,69

SMILES:

Cc1cc(Cl)ccc1OCCCC(=O)NO

Formula:

C11H14ClNO3

Pathway:

DNA Damage/DNA Repair,Chromatin/Epigenetic,Apoptosis

Target:

HDAC,HDAC,Apoptosis