Bioactivity:

CHIR-98014 is a selective GSK3 inhibitor; potentiate insulin activation of glucose transport and utilization in vitro and in vivo.

CAS nr:

252935-94-7

Purity:

98%

Molecular Weight:

486,31

SMILES:

c1cc(c(cc1Cl)Cl)c1nc(ncc1n1ccnc1)NCCNc1nc(c(cc1)[N+](=O)[O-])N

Formula:

C20H17Cl2N9O2

Pathway:

PI3K/Akt/mTOR signaling,Angiogenesis,Stem Cells,Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,PI3K/Akt/mTOR signaling,MAPK

Target:

GSK-3,Src,GSK-3,FGFR,Src,FGFR,S6 Kinase,S6 Kinase