Bioactivity:

GSK484 hydrochloride (GTPL8577) is a specifc and reversible peptidyl arginine deiminase 4 (PAD4) inhibitor. It demonstrates high-affinity binding to PAD4 with IC50s of 50 nM in the absence of Calcium.

CAS nr:

1652591-81-5

Purity:

98%

Molecular Weight:

510,03

SMILES:

Cl.COC1=CC(=CC2=C1N(C)C(=N2)C1=CC2=CC=CC=C2N1CC1CC1)C(=O)N1CC[C@@H](O)[C@@H](N)C1

Formula:

C27H30ClN5O3

Pathway:

Chromatin/Epigenetic

Target:

PAD