Bioactivity:

Dichloroacetate, a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 _M for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion channel axis, trigger apoptosis in cancer cells, and i

CAS nr:

2156-56-1

Purity:

98%

Molecular Weight:

150,92

SMILES:

C(C(=O)[O-])(Cl)Cl.[Na+]

Formula:

C2HCl2NaO2

Pathway:

Immunology/Inflammation,NF-_b,Metabolism,PI3K/Akt/mTOR signaling,Apoptosis,Metabolism

Target:

Reactive Oxygen Species,Reactive Oxygen Species,Reactive Oxygen Species,PDK,Apoptosis,Dehydrogenase