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TargetMol Chemicals

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TargetMol Chemicals Inc. specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.

TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, their lab allows them to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of their clients.

With TargetMol’s high-quality products & services, fast & efficient global supply chain and professional technical support, TargetMol believes they will help you shorten your research process and yield a more successful result.

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JAK1-IN-4 T15606

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Specifications

1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

JAK1-IN-4 is a selective JAK1 inhibitor (IC50s: 85 nM, 12.8 _M and >30 _M for JAK1, JAK2, and JAK3, respectively). JAK1-IN-4 inhibits STAT3 phosphorylation in NCI-H 1975 cells (IC50, 227 nM).

CAS nr:

2091134-35-7

Purity:

98%

Molecular Weight:

521,59

SMILES:

O=C(NC1=CC=CC2=C1NC=C2C3=C(C=NC(NC4=CN(N=C4OC)C)=N3)F)[C@H](N5CCN([C@@H](C5)C)C)C

Formula:

C26H32FN9O2

Pathway:

JAK/STAT signaling,Chromatin/Epigenetic,Stem Cells,Angiogenesis

Target:

JAK,JAK,JAK,JAK