Bioactivity:

Setipiprant is an orally available, selective CRTH2 antagonist (IC50: 6.0 nM). CRTH2 is a G protein-coupled receptor for prostaglandin (PGD2). PGD2 is produced by the mast cells and is a key mediator in various inflammatory diseases, including allergy and

CAS nr:

866460-33-5

Purity:

98%

Molecular Weight:

402,42

SMILES:

C1CN(CC2=C1N(C3=C2C=C(C=C3)F)CC(=O)O)C(=O)C4=CC=CC5=CC=CC=C54

Formula:

C24H19FN2O3

Pathway:

Endocrinology/Hormones,GPCR/G Protein,GPCR/G Protein,Immunology/Inflammation

Target:

GPR,GPR,Prostaglandin Receptor,Prostaglandin Receptor