Bioactivity:

PNU-142633 has anti-migraine efficacy. PNU-142633 is a high affinity and selective 5-HT1D receptor agonist (Kis of 6 nM and > 18 000 nM for human 5-HT1D receptor and human 5-HT1B receptor, respectively).

CAS nr:

187665-65-2

Purity:

98%

Molecular Weight:

422,52

SMILES:

O=C(C1=CC=C2C(CCO[C@H]2CCN3CCN(C4=CC=C(C(N)=O)C=C4)CC3)=C1)NC

Formula:

C24H30N4O3

Pathway:

GPCR/G Protein,Neuroscience

Target:

5-HT Receptor,5-HT Receptor