Bioactivity:

Gemcitabine is a DNA synthesis inhibitor (IC50s: 12, 18, 40, 92.7, 89.3 in Capan2, BxPC-3, Mia Paca-2, PANC-1, and PL-45 cells, respectively).

CAS nr:

122111-03-9

Purity:

98%

Molecular Weight:

299,66

SMILES:

Cl.Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)C2(F)F)c(=O)n1

Formula:

C9H11F2N3O4�HCl

Pathway:

DNA Damage/DNA Repair,Cell Cycle/Checkpoint,Autophagy,Apoptosis,DNA Damage/DNA Repair,Cell Cycle/Checkpoint

Target:

Nucleoside Antimetabolite/Analog,Nucleoside Antimetabolite/Analog,Autophagy,Apoptosis,DNA/RNA Synthesis,DNA/RNA Synthesis