Bioactivity:

AMG 837 calcium hydrate is a potent GPR40 agonist(EC50: 13 nM) with highly selective over GPR41, GPR43, and GPR120 (EC50 > 10,000 nM).

CAS nr:

1259389-38-2

Purity:

98%

Molecular Weight:

455,45

SMILES:

CC#CC(CC(=O)[O-])C1=CC=C(C=C1)OCC2=CC(=CC=C2)C3=CC=C(C=C3)C(F)(F)F.CC#CC(CC(=O)[O-])C1=CC=C(C=C1)OCC2=CC(=CC=C2)C3=CC=C(C=C3)C(F)(F)F.O.[Ca+2]

Formula:

Pathway:

Endocrinology/Hormones,GPCR/G Protein

Target:

GPR,GPR