Bioactivity:

MBM-17 is a potent inhibitor of NIMA-related kinase 2 (Nek2,IC50 of 3 nM).�It effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis.

CAS nr:

2083621-90-1

Purity:

98%

Molecular Weight:

480,56

SMILES:

NC(C(C=C1)=C(OCC2=CC=CC=C2)C=C1C3=CN=C4N3C=CC(C5=CN(CCN(C)C)N=C5)=C4)=O

Formula:

C28H28N6O2

Pathway:

Chromatin/Epigenetic,Cell Cycle/Checkpoint

Target:

Aurora Kinase,Aurora Kinase