Bioactivity:

Merbarone is a Type II DNA topoisomerase inhibitor. Merbarone inhibits the catalytic activity of human topoisomerase IIalpha by blocking DNA cleavage. Merbarone induces activation of caspase-activated DNase and excision of chromosomal DNA loops from the n

CAS nr:

97534-21-9

Purity:

98%

Molecular Weight:

263,27

SMILES:

S=C(NC(C1N(C2=CC=CC=C2)C=O)=O)NC1=O

Formula:

C11H9N3O3S

Pathway:

Target: