Bioactivity:

ROR_t Inverse agonist 3 is a potent, selective and orally active inverse agonist of ROR_(EC50s of 0.22 _M and 0.15 _M for hROR_ and ROR_t (human IL-17 cells), respectively).

CAS nr:

2364429-77-4

Purity:

98%

Molecular Weight:

616,56

SMILES:

CC(C)C1=NC2=C(C=CC=C2OCC3=C(Cl)C=CC(S(=O)(N4CCC[C@H]4C(NC)=O)=O)=C3Cl)C(C5=CN=CN5C)=C1

Formula:

C29H31Cl2N5O4S

Pathway:

Others

Target:

Others