Bioactivity:

VHL Ligand-Linker Conjugates 17 incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. VHL Ligand-Linker Conjugates 17 can be used in the synthesis of a series of PROTACs, such as ARD-266. ARD-266 is a highly potent androgen receptor

CAS nr:

T18873

Purity:

98%

Molecular Weight:

654,75

SMILES:

O=C(C[C@@H](C1=CC=CC=C1)NC([C@H]2N(C([C@H](C(C)C)C3=CC(C)=NO3)=O)C[C@H](O)C2)=O)N(CC4)CCC4C#CC5=CC=C(C(O)=O)C=C5

Formula:

C37H42N4O7

Pathway:

Others

Target:

Others