Bioactivity:

Torkinib (PP 242) is a selective and ATP-competitive mTOR inhibitor (IC50: 8 nM). It also inhibits mTORC1/2 (IC50s: 30/58 nM).

CAS nr:

1092351-67-1

Purity:

98%

Molecular Weight:

308,34

SMILES:

CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc12

Formula:

C16H16N6O

Pathway:

PI3K/Akt/mTOR signaling,PI3K/Akt/mTOR signaling,Autophagy,Apoptosis,Autophagy

Target:

mTOR,PI3K,Autophagy,Apoptosis,Mitophagy