Bioactivity:

Ro 18-3981 is an inhibition of myocardial Ca2+ channels. The KD value of Ro 18-3981 (1.0 nM) was similar to the IC50 value for blockade of ICa at a Vh of -20 mV (2.3 nM), i.e. at a level of near-maximal depolarization.

CAS nr:

103295-92-7

Purity:

98%

Molecular Weight:

523,6

SMILES:

O=C([O-])C1=C(C)(CCOCCC)NC(C)=C(C(CS(=O)(NC(C)C)=O)=O)C1C2=CC=CC([N+]([O-])=O)=C2

Formula:

C24H33N3O8S-

Pathway:

Target: