Bioactivity:

K-Ras ligand-Linker Conjugate 3 (Compound 001371) incorporates a ligand for K-Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 3 can be used in the synthesis of PROTAC K

CAS nr:

2378261-87-9

Purity:

98%

Molecular Weight:

944,15

SMILES:

O=C(N1[C@@H](CC#N)CN(C2=C3C(CN(C4=C5C=CC=CC5=CC=C4)CC3)=NC(OC[C@H]6N(C)C[C@H](OCCOCCOCCOCCOS(=O)(C7=CC=C(C)C=C7)=O)C6)=N2)CC1)OC(C)(C)C

Formula:

C49H65N7O10S

Pathway:

Others

Target:

Others