Bioactivity:

BH3I-2' is a cell-permeable BH3 mimetic. BH3I-2' induces apoptosis by specifically preventing BH3 domain-mediated interactions between pro-apoptotic and anti-apoptotic members of the Bcl-2 family, thereby blocking the interaction between Bcl-x and Bak BH3

CAS nr:

315195-18-7

Purity:

98%

Molecular Weight:

582,61

SMILES:

O=C(NC1=CC(S(=O)(C2=CC=C(Cl)C=C2)=O)=CC=C1Cl)C3=CC(Cl)=CC(I)=C3O

Formula:

C19H11Cl3INO4S

Pathway:

Target: