Bioactivity:

LXW7 TFA, a cyclic peptide containing Arg-Gly-Asp (RGD), is an integrin _v_3 inhibitor with an anti-inflammatory effect. LXW7 has a high binding affinity to _v_3 integrin (IC50: 0.68 _M). It increases the phosphorylation of VEGFR-2 and activation of ERK1/

CAS nr:

TP2148

Purity:

98%

Molecular Weight:

934,92

SMILES:

Formula:

C31H49F3N12O14S2

Pathway:

Cytoskeletal Signaling

Target:

Integrin