Bioactivity:

BFH772, a structure analogue of BAW2881, is a potent and selective VEGF inhibitor. BFH772 is highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM. BFH772 inhibits the ligand induced autophosphorylation of RET, PDGFR, and KIT kinases, wit

CAS nr:

890128-81-1

Purity:

98%

Molecular Weight:

439,39

SMILES:

c1cc(cc(c1)NC(=O)c1cccc2c1ccc(c2)Oc1ncnc(c1)CO)C(F)(F)F

Formula:

C23H16F3N3O3

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors

Target:

VEGFR,VEGFR