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Bioactivity:
SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-_ production in human monocytes (IC50: 1 _M).
CAS nr:
72873-74-6
Purity:
98%
Molecular Weight:
297,35
SMILES:
Fc1ccc(cc1)c1c(n2CCSc2n1)c1ccncc1
Formula:
C16H12FN3S
Pathway:
Apoptosis,MAPK
Target:
TNF,p38 MAPK