Ivacaftor T2588
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Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
Ivacaftor (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR (EC50: 25 nM) in Fisher rat thyroid cells, respectively.
CAS nr:
873054-44-5
Purity:
98%
Molecular Weight:
392,49
SMILES:
CC(C)(C)c1cc(c(NC(=O)c2c[nH]c3ccccc3c2=O)cc1O)C(C)(C)C
Formula:
C24H28N2O3
Pathway:
Membrane transporter/Ion channel,Autophagy
Target:
CFTR,Autophagy