Bioactivity:

Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier. It is a potent _4_2 nAChR agonist and inhibits NF-_B activation lower amyloid-_ (A_) production by preventing the _-cleavage of the amyloid precursor protein.

CAS nr:

T10318

Purity:

98%

Molecular Weight:

544,46

SMILES:

O=C(CC(C(O)=O)(O)CC(O)=O)O.O=C(CC(C(O)=O)(O)CC(O)=O)O.[C@@H]1(C2=CC=CN=C2)CC=CCN1

Formula:

C22H28N2O14

Pathway:

NF-_b

Target:

NF-_B