Bioactivity:

FRAX486 HCL is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.

CAS nr:

T6840L

Purity:

98%

Molecular Weight:

549,86

SMILES:

FC1=CC(NC2=NC=C3C(N(C(C(C4=CC=C(C=C4Cl)Cl)=C3)=O)CC)=N2)=CC=C1N5CCNCC5.[H]Cl

Formula:

C25H24Cl3FN6O

Pathway:

Cytoskeletal Signaling

Target:

PAK