Bioactivity:

Tofacitinib citrate is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).

CAS nr:

540737-29-9

Purity:

98%

Molecular Weight:

504,49

SMILES:

OC(=O)CC(O)(CC(O)=O)C(O)=O.C[C@@H]1CCN(C[C@@H]1N(C)c1ncnc2[nH]ccc12)C(=O)CC#N

Formula:

C22H28N6O8

Pathway:

Microbiology/Virology,Microbiology/Virology,Stem Cells,Angiogenesis,JAK/STAT signaling,Chromatin/Epigenetic,Microbiology/Virology,Apoptosis

Target:

Antibacterial,Antifungal,JAK,JAK,JAK,JAK,Influenza Virus,Apoptosis