Bioactivity:

Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 _M and has less active than the (-) enantiomer.

CAS nr:

133550-37-5

Purity:

98%

Molecular Weight:

308,33

SMILES:

C[C@@H](c1ccccc1)NC(/C(/C#N)=C/c(cc1)cc(O)c1O)=O

Formula:

C18H16N2O3

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis,JAK/STAT signaling

Target:

EGFR,EGFR,EGFR