Poziotinib hydrochloride T8758
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
Poziotinib hydrochloride irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors.�It is an orally bioavailable, quinazoline-based pan epiderma
CAS nr:
1429757-68-5
Purity:
98%
Molecular Weight:
527,8
SMILES:
Cl.COc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1OC1CCN(CC1)C(=O)C=C
Formula:
C23H22Cl3FN4O3
Pathway:
Tyrosine Kinase/Adaptors,Angiogenesis,JAK/STAT signaling
Target:
EGFR,EGFR,EGFR
