Bioactivity:

Vincristine binds irreversibly to microtubules (Ki: 85 nM) and spindle proteins in S phase of the cell cycle and interferes with the formation of the mitotic spindle.

CAS nr:

2068-78-2

Purity:

98%

Molecular Weight:

923,04

SMILES:

OS(O)(=O)=O.CC[C@]1(O)C[C@H]2C[N@@](C1)CCc1c([nH]c3ccccc13)[C@@](C2)(C(=O)OC)c1cc2c(cc1OC)N(C=O)[C@@H]1[C@]22CCN3CC=C[C@](CC)([C@@H]23)[C@@H](OC(C)=O)[C@]1(O)C(=O)OC

Formula:

C46H58N4O14S

Pathway:

Cytoskeletal Signaling,Apoptosis

Target:

Microtubule Associated,Apoptosis