Ruxolitinib T1829
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Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
Ruxolitinib is a potent and selective JAK1/2 inhibitor (IC50: 3.3/2.8 nM) and is relatively less selective for JAK3 (IC50: 322 nM).
CAS nr:
941678-49-5
Purity:
98%
Molecular Weight:
306,37
SMILES:
N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Formula:
C17H18N6
Pathway:
Stem Cells,Angiogenesis,JAK/STAT signaling,Chromatin/Epigenetic,Autophagy,Apoptosis,Tyrosine Kinase/Adaptors,Autophagy
Target:
JAK,JAK,JAK,JAK,Autophagy,Apoptosis,Tyrosine Kinases,Mitophagy