Bioactivity:

IACS-010759 is a potent inhibitor of complex I of OXPHOS with orally bioavailable. IACS-10759 effectively inhibits ATP production and oxygen consumption in isolated mitochondria, and inhibits the conversion of NADH to NAD+ in immunoprecipitated complex I

CAS nr:

1807523-99-4

Purity:

98%

Molecular Weight:

599,03

SMILES:

FC(F)(F)OC1=CC=C(C2=NOC(C3=NN(CC4=CC=CC(N5CCC(S(=O)(C)=O)CC5)=C4)C(C)=N3)=N2)C=C1.[H]Cl

Formula:

C25H26ClF3N6O4S

Pathway:

Target: