Bioactivity:

Naluzotan is an effective and selective amidosulfonamide 5-HT1A agonist with IC50 and Ki of appr 20 nM and 5.1 nM. Naluzotan is used for the treatment of anxiety and depression and is also a weak hERG K+ channel blocker (IC50: 3800 nM).

CAS nr:

740873-06-7

Purity:

98%

Molecular Weight:

450,64

SMILES:

CC(NC1=CC=CC(N2CCN(CCCCNS(=O)(CC3CCCCC3)=O)CC2)=C1)=O

Formula:

C23H38N4O3S

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors

Target:

BTK,BTK