Bioactivity:

AST2818 mesylate,is an irreversible tyrosine kinase inhibitor that selectively inhibits EGFR mutations, especially T790M.

CAS nr:

2130958-55-1

Purity:

98%

Molecular Weight:

664,7

SMILES:

CS(O)(=O)=O.CN(C)CCN(C)c1nc(OCC(F)(F)F)c(Nc2nccc(n2)-c2cn(C)c3ccccc23)cc1NC(=O)C=C

Formula:

C29H35F3N8O5S

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis,JAK/STAT signaling

Target:

EGFR,EGFR,EGFR