Bioactivity:

RIPK1-IN-7 is a potent and selective inhibitor of RIPK1(Kd of 4 nM and an enzymatic IC50 of 11 nM),andexhibits excellent antimetastasis activity in the experimental B16 melanoma lung metastasis model.

CAS nr:

2300982-44-7

Purity:

98%

Molecular Weight:

481,47

SMILES:

NC1=C2C(N(CC)C=C2C3=CC(CCN4C(CC5=CC=CC(OC(F)(F)F)=C5)=O)=C4C=C3)=NC=N1

Formula:

C25H22F3N5O2

Pathway:

NF-_b,Apoptosis

Target:

RIP kinase,RIP kinase