Bioactivity:

XL-784 is a selective inhibitor of matrix metalloproteinases (MMP)(IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1,MMP-2,MMP-3,MMP-8,MMP-9,MMP-13,respectively).

CAS nr:

1224964-36-6

Purity:

98%

Molecular Weight:

549,93

SMILES:

O=C(N1CC(C(NO)=O)N(S(=O)(C2=CC(F)=C(OC3=CC=C(Cl)C=C3)C(F)=C2)=O)CC1)OCCOC.[0.5Mg2+]

Formula:

C21H22ClF2N3O8S

Pathway:

Proteases/Proteasome

Target:

MMP