Bioactivity:

(R)-(-)-Rolipram is the R-enantiomer of Rolipram. Rolipram is a selective inhibitor of phosphodiesterases PDE4(IC50 of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively).

CAS nr:

85416-75-7

Purity:

98%

Molecular Weight:

275,34

SMILES:

O=C1NC[C@@H](C2=CC=C(OC)C(OC3CCCC3)=C2)C1

Formula:

C16H21NO3

Pathway:

PI3K/Akt/mTOR signaling,DNA Damage/DNA Repair

Target:

DNA-PK,DNA-PK