Bioactivity:

GSK690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.

CAS nr:

937174-76-0

Purity:

98%

Molecular Weight:

425,48

SMILES:

CCn1c(nc2c1c(OC[C@H]1CCCNC1)cnc2C#CC(C)(C)O)c1nonc1N

Formula:

C21H27N7O3

Pathway:

Cytoskeletal Signaling,Chromatin/Epigenetic,PI3K/Akt/mTOR signaling,Autophagy,Cytoskeletal Signaling,PI3K/Akt/mTOR signaling,Proteases/Proteasome

Target:

PKC,PKC,AMPK,Autophagy,Akt,Akt,Serine Protease