Bioactivity:

Ro 90-7501 is an amyloid _42 fibril assembly inhibitor (EC50: 2 _M). Ro 90-7501 inhibits ATM phosphorylation and DNA repair. Ro 90-7501 also inhibits PP5 in a TPR-dependent manner. RO 90-7501 selectively enhances TLR3 and RLR ligand-induced IFN-_ gene exp

CAS nr:

293762-45-5

Purity:

98%

Molecular Weight:

340,38

SMILES:

NC1=CC=C2C(N=C(C3=CC=C4C(N=C(C5=CC=C(N)C=C5)N4)=C3)N2)=C1

Formula:

C20H16N6

Pathway:

PI3K/Akt/mTOR signaling,DNA Damage/DNA Repair

Target:

ATM/ATR,ATM/ATR