Bioactivity:

Hellebrigenin has anti-hepatoma activities, it induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt. Hellebrigenin exhibites moderate to strong activity against human HL-60, SF-295, MDA-MB-435, an

CAS nr:

465-90-7

Purity:

98%

Molecular Weight:

416,51

SMILES:

[H][C@@]12CC[C@]3(O)C[C@@H](O)CC[C@]3(C=O)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@]21O)c1ccc(=O)oc1

Formula:

C24H32O6

Pathway:

DNA Damage/DNA Repair,Chromatin/Epigenetic,Cytoskeletal Signaling,PI3K/Akt/mTOR signaling,Cell Cycle/Checkpoint

Target:

PARP,PARP,Akt,Akt,CDK