Bioactivity:

TAK-659 is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent toward both SYK and FLT3.

CAS nr:

1952251-28-3

Purity:

98%

Molecular Weight:

380,85

SMILES:

Cn1cc(cn1)c1nc(c(c2c1C(=O)NC2)F)N[C@@H]1CCCC[C@@H]1N.Cl

Formula:

C17H22ClFN6O

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Angiogenesis,Stem Cells,Angiogenesis,JAK/STAT signaling,Chromatin/Epigenetic,Tyrosine Kinase/Adaptors

Target:

FLT,FLT,VEGFR,VEGFR,Syk,Syk,JAK,JAK,JAK,JAK,Tyrosine Kinases