Bioactivity:

The dose-dependent effect of PF-915275 on the conversion of cortisone to cortisol in primary human and monkey hepatocytes (EC50: 20 and 100 nM, respectively). PF-915275 is an effective and selective human 11_-hydroxysteroid dehydrogenase type 1 inhibitor

CAS nr:

857290-04-1

Purity:

98%

Molecular Weight:

350,39

SMILES:

N#CC1=CC=C(C2=CC=C(S(NC3=NC(N)=CC=C3)(=O)=O)C=C2)C=C1

Formula:

C18H14N4O2S

Pathway:

Others

Target:

Others