Bioactivity:

GW6471 is an antagonist of PPAR_ with IC50 of 0.24 _ M. GW6471 enhances the binding affinity of the PPAR _ ligand-binding domain to the co-repressor proteins SMRT and NCoR.

CAS nr:

880635-03-0

Purity:

98%

Molecular Weight:

619,67

SMILES:

CCC(NC[C@@H](N/C(C)=C\C(C1=CC=C(C(F)(F)F)C=C1)=O)CC2=CC=C(OCCC3=C(C)OC(C4=CC=CC=C4)=N3)C=C2)=O

Formula:

C35H36F3N3O4

Pathway:

DNA Damage/DNA Repair,Metabolism

Target:

PPAR,PPAR