Bioactivity:

Rotigaptide TFA is a novel and specific modulator of Cx43 and is a potent AAP. Rotigaptide prevents the uncoupling of Cx43-mediated gap junction communication and normalizes cell-to-cell communication during acute metabolic stress.

CAS nr:

T16790L

Purity:

98%

Molecular Weight:

SMILES:

C[C@H](C(=O)NCC(=O)N)NC(=O)CNC(=O)[C@H]1C[C@@H](CN1C(=O)[C@H]2CCCN2C(=O)[C@@H](CC3=CC=C(C=C3)O)NC(=O)C)O.OC(C(F)(F)F)=O

Formula:

Pathway:

Cytoskeletal Signaling

Target:

Gap Junction Protein