Bioactivity:

BI-0115 is a selective small molecule inhibitor of LOX-1 that blocks cellular uptake of oxLDL. It binding triggers receptor inhibition by formation of dimers of the homodimeric ligand binding domain. The structure of LOX-1 bound to BI-0115 shows that inte

CAS nr:

4929-23-1

Purity:

98%

Molecular Weight:

287,747

SMILES:

O=C1N(CCC)C2=CC=CN=C2NC3=C1C=CC(Cl)=C3

Formula:

C15H14ClN3O

Pathway:

Metabolism

Target:

Lipoxygenase