Bioactivity:

JNJ-61432059 is an oral active and selective negative modulator of AMPAR associated with trans-membrane AMPAR regulatory protein (TARP) _-8 (pIC50: 9.7 for GluA1/_-8).

CAS nr:

2035814-50-5

Purity:

98%

Molecular Weight:

443,47

SMILES:

OC1CCN(C2=NC=CC3=C(C4=CC=C(NC(C5)=O)C5=C4)C(C6=CC=C(F)C=C6)=NN32)CC1

Formula:

C25H22FN5O2

Pathway:

Membrane transporter/Ion channel,Neuroscience

Target:

iGluR,iGluR