Bioactivity:

GSK2656157 is a highly specific and ATP-competitive PERK inhibitor (IC50: 0.9 nM) in a cell-free assay. The selectivty is 500-fold higher against a panel of 300 kinases.

CAS nr:

1337532-29-2

Purity:

98%

Molecular Weight:

416,45

SMILES:

Cc1cccc(CC(=O)N2CCc3c2ccc(-c2cn(C)c4ncnc(N)c24)c3F)n1

Formula:

C23H21FN6O

Pathway:

Autophagy,Apoptosis,Apoptosis

Target:

Autophagy,PERK,Apoptosis