Bioactivity:

ARQ-531 is a potent and orally active BTK inhibitor with potential antineoplastic activity, with IC50s of 0.85 nM and 0.39 nM for WT-BTK and C481S-BTK, respectively.

CAS nr:

2095393-15-8

Purity:

98%

Molecular Weight:

478,93

SMILES:

O=C(C1=CC=C(OC2=CC=CC=C2)C=C1Cl)C3=CNC4=NC=NC(N[C@H]5CO[C@H](CO)CC5)=C43

Formula:

C25H23ClN4O4

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors

Target:

BTK,BTK