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Bioactivity:
AF-353, an effective and orally bioavailable antagonist of the P2X3/P2X2/3 receptor, inhibits human and rat P2X3 (pIC50= 8.0).
CAS nr:
865305-30-2
Purity:
98%
Molecular Weight:
400,21
SMILES:
COc1cc(C(C)C)c(Oc2cnc(N)nc2N)cc1I
Formula:
C14H17IN4O2
Pathway:
Membrane transporter/Ion channel,Neuroscience
Target:
P2X Receptor,P2 Receptor