Bioactivity:

Cobimetinib is a selective inhibitor of mitogen-activated protein kinase kinase (MEK) (IC50: 0.9 nM). Cobimetinib specifically binds to and inhibits the catalytic activity of MEK1, resulting in inhibition of extracellular signal-related kinase 2 (ERK2) ph

CAS nr:

934660-93-2

Purity:

98%

Molecular Weight:

531,32

SMILES:

C1CCN[C@@H](C1)C1(CN(C1)C(=O)c1c(c(c(cc1)F)F)Nc1c(cc(cc1)I)F)O

Formula:

C21H21F3IN3O2

Pathway:

MAPK,Apoptosis

Target:

MEK,Apoptosis