Bioactivity:

Sabutoclax(BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 _M, 0.32 _M, 0.20 _M and 0.62 _M, respectively.

CAS nr:

1228108-65-3

Purity:

98%

Molecular Weight:

700,78

SMILES:

CC1=C(C(=C2C=C(C(=C(C2=C1)C(=O)NC[C@H](C)C3=CC=CC=C3)O)O)O)C4=C(C=C5C(=C4O)C=C(C(=C5C(=O)NC[C@H](C)C6=CC=CC=C6)O)O)C

Formula:

C42H40N2O8

Pathway:

Apoptosis,Angiogenesis,Tyrosine Kinase/Adaptors,Cytoskeletal Signaling

Target:

BCL,Bcr-Abl,Bcr-Abl,Bcr-Abl