Bioactivity:

SGX-523 is a selective Met inhibitor (IC50: 4 nM), no inhibitory to Abl, BRAFV599E, p38_, and c-Raf.

CAS nr:

1022150-57-7

Purity:

98%

Molecular Weight:

359,41

SMILES:

c1cnc2c(c1)cc(cc2)Sc1n2c(nn1)ccc(n2)c1cnn(c1)C

Formula:

C18H13N7S

Pathway:

MAPK,MAPK,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Cytoskeletal Signaling

Target:

Raf,p38 MAPK,c-Met/HGFR,Bcr-Abl,Bcr-Abl,Bcr-Abl